Fibrin sealants provide rapid and effective haemostasis, reduce the need for coagulation factor supplementation, promote tissue sealing and wound healing and allow the reduction in medical costs. Fibrin sealants thus offer both the patients and surgeons great benefits that enhance the overall outcome of many surgical interventions. Platelet derived products too, have a profound impact on tissue injury and bone grafting through the release of several growth factors from the platelet granules.