Multiple sclerosis (MS) is a serious neurological disease whichaffects patients and their environment negatively. Movement, balance andwalking impairments related to demyelination, axonal damage and theformation of sclerosis plaques in cerebral hemispheres, brain stem andspinal cord are wide spread in Multiple sclerosis patients. This study wasdesigned to assess postural stability and gait abnormalities in patientswith multiple sclerosis and included forty MS patients and forty controlsubjects, which were subjected to laboratory and radiologicalinvestigations, clinical balance scales and posturography tests. Theperformance of MS patients relative to control was poor in all balancescales and posturography tests. Among MS patients, relapsing remittingform was better in performance than the progressive forms.