Abnormal uterine bleeding is one of the most frequent gynecologic problems. Abnormal uterine bleeding may involve any disturbance of regularity, frequency, duration or volume of menstrual flow. 80% of abnormal uterine bleeding are due to hormonal disorders, called dysfunctional uterine bleeding, the others are of organic causes. Disorders of the female genital tract caused by endocrine disturbances commonly lead to two presenting complaints: Dysfunctional uterine bleeding and infertility. Secondary ovarian dysfunction may be caused by hypothalamic-pituitary dysergulation, hyperprolactinemia, thyroid disorders and hyperandrogenemia. This study showed that there were significant increase in serum total T3, free T3 and total T4 and significant decrease in serum TSH hormone among the group of menorrhgia when compared to both oligo-hypomenorrhea and control groups.From the results of the present study we can conclude that impaired thyroid function plays an intimate role on the hypothalamic-pituitary-ovarian axis and this is reflected as dysfunctional uterine bleeding. It is highly recommended to add thyroid function tests as a routine in all cases of dysfunctional uterine bleeding.