Objective. Our aim was to determine the correlation between maternal urinary tract infection during pregnancy and preterm labor. Methods. Prospective case control study in 50 preterm babies and their mothers and 50 mothers in full-term labor were performed. Urine sample was obtained from the mothers of both case and control groups and screened for infection, compared to its relation to prematurity. And blood culture was done to babies of the mothers of the case group to determine the correlation between neonatal sepsis and maternal UTI. And statistically analyzed. Results. We evaluated urinary tract infection in 50 mothers in preterm labor (case group) and 50 mothers in full-term labor (control group) and found that of 50 patients of the case group, 8 (16.0%) had urinary tract infection and of 50 patients of the control group, 2 (4.0%) had urinary tract infection and out of 50 babies in the case group, 4 (8.0%) had positive blood culture. there was a statistically significant positive (direct) correlation between maternal urinary tract infection and preterm labor and neonatal sepsis. Conclusions: maternal urinary tract infection during pregnancy shows statistically significant positive (direct) correlation with preterm labor and prematurity show statistically significant positive (direct) correlation with neonatal sepsis.