Idiopathic immune thrombocytopenic purpura (ITP) known as primary ITP or autoimmune thrombocytopenic purpura is defined as isolated thrombocytopenia with normal bone marrow in absence of other causes of thrombocytopenia . ITP is primarily a disease of increased peripheral platelets destruction, with most patients having antibodies to specific platelet membrane glycoproteins. In about 30% of cases of ITP, antiphospholipid antibodies (APLA) are present and in about 20% of antiphospholipid syndrome (APS), thrombocytopenia is detected. Interestingly, some ITP patients with persistent APLA may later develop thrombotic complications particularly when platelet count normalizes after corticosteroid therapy or splenectomy . It was suggested by some studies that the persistent presence of APLA in patients with ITP might be an important risk factor for the development of APS. Significantly high ACA IgM , ACA IgG and antiβ2glycoprotein IgG mean concentrations were found in chronic ITP cases compared with acute cases or controls .