Background: Multislice CT is a recent development in the spiral CT that allows ECG-gated complete coronary coverage in a reasonable time.Objectives: To investigate the ability of new generations of MSCT coronary angiography, using the 64-slice CT scanners to detect high-grade coronary artery stenosis and occlusion and to evaluate the vascular conduits in patients with previous CABG operations.Conclusion: CT angiography permits non-invasive coronary imaging, particularly at the proximal coronary segments. However, because of the limited temporal & spatial resolutions and the various artifacts associated with data creation & reformation, post-processing methods, and image interpretation, MSCT angiography is not ready to replace conventional coronary angiography at this time. In view of the high NPV, patients without significant CAD would be selected accurately at CT, and hence, avoiding the unnecessary invasive coronary angiography.