Background: Fetal kidney weight cannot be measured in utero, renalvolume measured by U/S is a valid substitute. With the latestdevelopments in the field of three dimensional U/S, accurate assessmentof the fetal organ volume has become feasible and this technique hasgained widespread application in different medical fields.We also aimed to examine the association of renal artery, umbilical arterywith fetal kidney volume.Objective: Intrauterine growth restriction may lead to renal disease andhypertension in adult life. This study was performed to determinewhether renal volume differs between fetuses that are intrauterine growthrestricted and fetuses that are not. We also aimed to examine theassociation of fetal blood flow parameters with the fetal renal volume.Design: Prospective randomized descriptive study.Setting: Department of Obstetrics and Gynecology-Cairo UniversityHospitals-Kasr El Aini.Patients and methods: Examinaton of 120 pregnant women between 36-40 weeks of gestation. Women was divided into 2 groups; mothers withIUGR (group A, n=60) and mothers within normal range fetal biometryi.e. control group (group B, n=60). In all participants, total renal volumewas measured using 3D U/S and umbilical as well as fetal renal arteryDoppler which was calculated using color Doppler technique. Allmeasured parameters were compared to fetal growth stage and correlatedto the total renal volume.Results: The mean total fetal renal volume was 15.3 3.4 in group A and16.33.8 in group B. (p value >0.05). Estimated fetal weight werepositively correlated with the total renal volume "TRV" in both groups"r=0.2 in Gp B, and 0.4 for Gp A, with a statistically significant p valuefor both gorups. Renal artery pulsitilaty index (PI)and resistance index(RI) showed no significant correlation with the TRV in both groups , PI"r = 0.03 p= 0.79 in Gp A, and RI "r=0.09 p=0.4 in Gp A ,and PI "r=0.1 p=0.3in Gp B, and RI "r = 0.09 p = 0.4 for Gp B"Conclusion: The conclusion of our study is that intrauterine growthrestriction appears to be associated with a decrease in the estimated fetalweight with no significant difference in the fetal renal volume betweenthe two groups this study supports the hypothesis that intrauterine growthrestriction may be linked to renal disease and hypertension in late life.