Background: Obesity in children and adolescents increases the risk for various cardiovascular problems. Increase in BMI is often an independent risk factor for the development of elevated blood pressure and clustering of various cardiovascular risk factors in metabolic syndrome.Objective: To detect early cardiovascular risk factor in obese children and adolescents by: (1) Measuring Troponin I levels and Lipid profile. (2) ECG changes including QT interval & QT dispersion. (3) Echocardiographic study including Tissue Doppler.Methods: In present cross-sectional study we evaluated 32 children and adolescent with obesity and 30 healthy controls. Their ages ranged from 6- 19 years. Studied children were subjected to: anthropometric measurements, Lipid profiles assessment, serum Troponin I level measurement and Echocardiographic evaluation to asses LV dimensions, systolic and global function. ECG changes were recorded. TDI to measure Mitral annular S', A` and E' velocities. LV systolic, diastolic and time to peak systolic velocities were recorded also at lateral and septal walls. Results: The mean of serum of Troponin I 0.14± 0.39ng/ml ranged from (0.0- 1.9) which is consider high, there was a significant positive correlation between Troponin and SBP in cases (r = 0.359, p = 0.044). There was highly significant increase in serum TCh, TG and a significant decrease in HDL in obese. QRS and PR interval were significantly greater in obese (p<0.049, p<0.01 respectively). Furthermore, there was no significance difference in QT c, QT dispersion, HR (p=0.9, p=0.7, p=0.3, respectively).The IVSd, LVEDD, LVESD, LVPWd, LV mass, LV index significantly greater in obese (p=0.006, p<0.001, p<0.001,p= 0.003,p<0.001,p<0.001respectively).Conclusion: Obese children are at increased risk of cardiovascular disease at adulthood; so efficient clinical prevention and intervention programs are essentially needed in obese children.