the aim of this work : is to correlate Body Mass Index (BMI) with two measures of functioning (the Short Form 36 Health survey physical function subscale and Valued Life Activities Disability Questionnaire) in female patients with SLE and Relation between Body Mass Index and functioning measures with various disease parameters including disease activity index (SLEDAI) and disease damage score (SLICC).Patient and methods: This study included 70 female patients suffering from SLE diagnosed according to American College of Rheumatology (ACR) classification criteria of SLE, in addition to 35 healthy individuals serving as a control group.All participations were subjected to full history taking, thorough clinical examination , including BMI ,and Function was detected using VAL( and SF-36,SLE laboratory parameters including lipid profile , disease activity index using SLEDAI and disease damage score using SLICC were evaluated .Results: the quality of life and functional capacity were worse in SLE group than in Control group. This difference was statistically significant when using VAL (Mean VAL in SLE patients was 28.41 and in Controls was 9.9 and P = 0.000).Obese SLE patients were worse than Non-Obese SLE in quality of life and Functional capacity when using VAL (Mean VAL in Obese SLE was 29.49 and in Non-Obese SLE was 27.06) and SF-36( mean SF-36 was 88.91 in Obese-SLE and was 89.41 in Non-Obese SLE) but this difference was non significant.Total VAL showed statistically significant Correlation with age (P = 0.003).Conclusion: We can state that there is non significant association of increased BMI with impaired functional capacity in female.