The occulomotor also supplies the inferior oblique muscle. The superior oblique is supplied by the trochlear nerve Tenon’s capsule is a thin fascial membrane that envelops the globe and separates it from the orbital fat. The origin of the extraocular muscles pierces this sheath. The eye receives sensory supply from the ophthalmic branch of the trigeminal nerve (cranial V). We can conclude that peribulbar and sub-Tenon’s regional anesthesia of the orbit during cataract surgery are safe procedures if blindly applied. Ultrasonography-guided needle (or cannula) injection doesn’t add to the safety and/or efficacy of the procedure. Peribulbar block using 5 ml of anesthetic drug seems less than required in almost 25% of cases, thus raising the injected volume up to 10 ml may be a better choice to guarantee a satisfactory degree of akinesia. Therefore, ultrasound guidance is not an advantage in orbital regional anesthesia; whether administered by the peribulbar or sub-Tenon’s technique.