This study demonstrates that real time ultrasound guided TPVB proved to be a simple and safe procedure in providing effective reliable analgesia, together with reduction of postoperative pain scores and postoperative opioid requirements together with their systemic side effects. Real time imaging during injection of the local anesthetic allows the operator to assess its spread and adjust the position of the needle tip as necessary to ensure placement of local anesthetic solution around all the appropriate nerves.breast cancer is still the most common cancer among women, and most of these women require breast surgery to remove the primary tumour and axillary staging or dissection