Purpose: To assess the postoperative macular reattachment through OCT in eyes treated due to macula-off rhegmatogenous retinal detachment, as well as to verify if there is a statistically relevant relation between the persistence of a subfoveal detachment and poor post-operative functional recovery. Methods: Forty-nine eyes of 49 patients were enrolled and examined in a prospective study. Exclusion criteria were the following: History of detachment longer than 7 days, Re-detachment, Tractional retinal detachment, Strabismus, Glaucoma, Amblyopia, Preexisting macular disease, Vitreous hemorrhages, Vascular occlusion, Uveitis. Results: After surgery, despite the macular reattachment assessed ophthalmoscopically, the OCT examination showed macular subretinal fluid persistence in 18/49 of cases. There were improvements in visual acuity with decrease of SRF amount. Persistent SRF was not the only detectable cause for bad vision prognosis. Conclusions. Delayed or incomplete visual recovery after uncomplicated surgery for macula-off retinal detachment may be related not only to persistent subretinal fluid, but also to other pathological changes.