The maintenance of a patent airway is one of the fundamental responsibilities of every anesthesiologist. Difficult intubation associated with difficult mask ventilation is responsible for a large proportion of anesthesia-related complications that may result in permanent disability or even death. When an airway problem is encountered, anesthesiologist should use the technique that he is most familiar or experienced with to gain control of the situation. Anticipating difficult airway is the most important issue in difficult airway management. For achieving this we need to be familiar with the anatomy of the airway, airway examination and assessment, ASA algorithm for difficult airway management, and the equipment that must be available for difficult airway management. Supraglottic Airway Devices are devices that ventilate patients by delivering anesthetic gases/oxygen above the level of the vocal cords and are designed to overcome the disadvantages of endotracheal intubation as: soft tissue, tooth, vocal cords, laryngeal and tracheal damage, exaggerated hemodynamic response, barotrauma, etc. The advantages of the supraglottic airway devices include: avoidance of laryngoscopy, less invasive for the respiratory tract, better tolerated by patients, increased ease of placement, improved hemodynamic stability in emergence, less coughing, less sore throat, hands free airway and easier placement by inexperienced personal.