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Assessment of saccular function using vestibular evoked myogenic potentials in children with sensorineural hearing loss

Thesis

Last updated: 06 Feb 2023

Subjects

-

Tags

Audiology

Advisors

El-Abd, Sherin M. , Selim, Muna H. , El-Manawi, Sherif M.

Authors

Beyatris, Murquss Yousuf

Accessioned

2017-07-12 06:40:32

Available

2017-07-12 06:40:32

type

M.Sc. Thesis

Abstract

The aim of this work was to investigate saccular function using cervical vestibular evoked myogenic potentials (cVEMPs) in children with congenital or early acquired sensorineural hearing loss (SNHL). Design: Descriptive cross sectional study. Subjects and Methods: This study was conducted on 30 children with different degrees of SNHL with normal middle ear function and 25 age and gender matched normal hearing children. All the subjects' age ranged from 5-18 years. For each child, the following were administrated; history taking, otologic examination, basic audiological evaluation in the form of pure tone audiometry (PTA) and immittancemetry, air conducted cVEMPs and computerized tomography (CT scan) of the temporal bone. Results obtained from the two groups were then compared. In addition, correlation studies between all obtained results were carried out. Results: There was a statistically non- significant difference between the patients and the controls regarding P13 and N23 latencies and P13-N23 amplitude and VEMP threshold results revealed a highly significant difference. VEMP measurements in relation to gender within the patient group revealed that VEMP threshold was the only positive outcome that revealed a significant difference and was higher in females. There was a highly significant positive correlation between hearing loss and VEMP threshold among the patient groups with different degrees of hearing losses. There was a significant positive correlation between age and P13 and N23 latency among the patient group. Conclusion: In this study, SNHL was associated with saccular dysfunction in pediatric population in the form of decreased P13-N23 amplitudes and elevated VEMP thresholds. Females presented with higher VEMP threshold values than males and VEMP latencies appear to increase with age. An increase in hearing loss is associated with an increase in VEMP threshold and VEMP amplitude appears to decrease with hearing loss regardless of its degree. We recommend including VEMPs in the battery of evaluation of children with SNHL to detect early subtle changes in saccular function. Further research on the genes causing SNHL and its relation to VEMP findings are worth undertaking.

Issued

1 Jan 2012

DOI

http://dx.doi.org/10.21473/iknito-space/35564

Details

Type

Thesis

Created At

28 Jan 2023