Obesity in children and adolescents has become an increasing clinical and public health concern. Its prevalence has increased significantly worldwide with an alarming rise of its co-morbidities that elevate the cardiovascular risk of affected people. Neck circumference (NC) has been shown to be an indicator of central adiposity and as a new screening method for measurement of obesity among children. Among those comorbidities are cardiometabolic comorbidities and metabolic syndrome which are due to impairment of systolic, diastolic blood pressure values, HDL, LDL, cholesterol, triglycerides, glucose and insulin level which indicates insulin resistance. The present study was a cross-sectional case-control study done in Diabetes Endocrine and Metabolism Pediatric Unit (DEMPU), Pediatric Hospital, Cairo University. It included 50 obese children (BMI ≥ 95th percentile for age and sex) and 50 non obese age and sex matched children who were taken as controls.