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Transcranial Doppler in monitoring management of sub-arachnoid haemorrhage

Thesis

Last updated: 06 Feb 2023

Subjects

-

Tags

Critical Care Medicine

Advisors

El-Badri, Mahmoud , Aly, Sherin , El-Qaffass, Khaled

Authors

Yasin, Ahmad

Accessioned

2017-04-26 12:37:43

Available

2017-04-26 12:37:43

type

M.Sc. Thesis

Abstract

Introduction: Subarachnoid hemorrhage (SAH) is defined bleeding into the subarachnoid space between the arachnoid membrane and the pia matter surrounding the brain. Cerebral vasospasm remains the most significant and most common (40% to 97%) complication and following subarachnoid hemorrhage. Transcranial Doppler one of emerging technique ; but despite the large body of evidence testifying application of transcranial Doppler for monitoring patients with subarachnoid HGE, for early prediction of vasospasm before development of ischaemic neurological deficit, the true value of this technique as sensitive predictor alone for diagnosing clinical vasospasm still mater of debate. We aimed at evaluation role of TCD in monitoring pts with SAH. Methods: our study was carried out on 30 patients diagnosed to have acute subarachnoid hemorrhage presented within 48 hrs (confirmed by CT brain) and our patients were divided into two groups : Group A includes 15 patients that were monitored by both the usual standard clinical and neurological evaluation that is normally used in the treatment of SAH. Group B includes 15 patients that were subjected to continuous non-invasive Trans-cranial Doppler (TCD) monitoring from days (4-21) after SAH, it will be done on alternative day. Results: 30 % of pts developed DIND maximum before day 10 prevalence of female (63.3%) to male (36.7%), and HTN (73.3%) to DM (13.3%) as premorbid condition. TCD is useful technique to predict clinical vasospasm when peak systolic velocity in MCA (>172 cm /sec),with sensitivity >60% and specificity 88%). We found also no increase in incidence of occurrence of DIND with increase H and H classes which means more deterioration in neurological condition(55% of pt with DIND were HESS and HUNT grade 1 and 45% were grade (2). So, H and H evaluation could not predict clinical vasospasm alone before occurrence. Conclusion: TCD useful tool for early prediction of DIND in SAH pts.

Issued

1 Jan 2011

DOI

http://dx.doi.org/10.21473/iknito-space/33338

Details

Type

Thesis

Created At

28 Jan 2023