Preterm labor is a common obstetric problem and a major cause of perinatal mortality. The exact cause of preterm labor remains unclear and there are many risk factors as socioeconomic status and life style factors of the mother. There are many methods of prediction like ultrasound evaluation The main tools that play an important role in the management of preterm labor are tocolytic therapy, antibiotics and corticosteroids. The prevention of preterm birth depends mainly on identification of women with risk factors and early intervention in order to get better survival outcomes with least possible handicapping.