This assay study the anesthetic management of patients with solid organ transplantation undergoing a non-transplant surgery. It comprises five chapters:-•First chapter talks about phathophysiological changes occurring to the post-transplant recipients.•Second chapter deals with the immunosuppression and its complications.•Third chapter lists complications that may occur to the post-transplant recipients. •Fourth chapter deals with anesthetic managements preoperatively, intraoperatively and postoperatively for post-transplants recipients undergoing a non-transplant surgery.•Fifth chapter highlights special situation such as post-transplantation in pediatrics, pregnancy in transplant recipients, laparoscopy and trauma in transplant recipients.