This work is intended to compare the effects of 3 different ways of reperfusion: Thrombolytic therapy using SK with (primary PCI and facilitated PCI and stenting) in pts with AMI using the technique of TDI to evaluate the extent of RWMA before and after intervention. We studied 25 pt with AMI (21 M, 4F). Six pts received Sk., 11 were subjected to 1ry stenting to IRA and 8 had facilitated PCI. Compared to control group, those with acute anterior MI exhibited significantly basal wall lower peak S wave, lower E waves and lower E/A ratio. Compared to pts who received SK, those subjected to primary PCI exhibited significantly greater immediate % improvement in the anterior basal wall in terms of higher peak S (25.8% vs 4.4%). Also pts subjected to facilitated PCI demonstrated significantly higher % improvement in anterior basal wall in terms of higher peak S (18.4% vs 4.4%).