Thirty patients with Hepatic encephalopathy were referred to the Hepatology Department in Ahmed Maher Teaching Hospital during the years 2000/2002. All the patients subjected to the following,Thorough history analysis as well as general, abdominal examination, Neurological evaluation, Lab Investigations; included full blood picture included RBC count, WBC count, platelets count & prothrombin time & concentration. Liver function; including serum bilirubin, serum transaminases (AST&ALT), renal function tests, blood sugar and Na, K& Ammonia.-Electroencephalography (EEG) and bilateral median nerve SEPs. Patients of hepatic encephalopathy subdivided according to the level of consciousness into Stage O including two patients, stage I including six patients, stage II including eight patients, stage III including ten patients and stage IV including four patients.Ammonia level was statistically correlated with conscious level, EEG and median nerve SEPs. Blood ammonia level was observed to increase with progression of Hepatic encephalopathy from stage I to stage IV. Increased blood ammonium levels correlated closely with episodes of Stupor of HE, associated with delayed N70 and prolongation of N20-N70 IPLs and abnormal changes of EEG. positive correlation between abnormal changes of EEG and conscious level of patients was statistically observed. Positive correlation between median nerve SEPs and conscious level of hepatic encephalopathy in different stages of diseases was also present.