PONV is considered a common complication after surgery. It results from factors related to anesthesia and other related to surgical procedures. Incidence of PONV varies with gender of the patients, age.. etc. Consequence of PONV as physical, metabolic …etc. Pharmacological methods used for prevention of PONV include drugs like Benzamide Butyrophenones, 5 HT3 antagonists. Recently combination of antiemetics is used as it is proved by studies that it more potent than sole antiemetic.