Patient satisfaction survey (PSS) could measure the quality of care and prepare advocacy material as policy brief that guide decisions for quality improvement. In cancer institute, conduction of PSS and using its findings is challenging due to the wide spectrum of cancer epidemiology and management strategies. The objectives of the study were to identify cancer patients' impression and attitude towards hospital services, highlight the items of quality of care that need intervention by surgery departments presented to policymakers as policy-brief, and measure the impact of interventions conducted by surgery staff on patient's satisfaction. Methods: The study was an operations research, pretest-posttest separate sample (n=250 for pretest and n=150 for posttest) intervention study conducted in the National Cancer Institute-Surgery inpatient units (6 units). Structured interview was done, using pre-tested questionnaire form, at time of discharge of inpatients from the hospital. The pre-intervention PSS findings had been analyzed and presented as policy brief to the Surgery Department Staff members 'Board. Interventions conducted by the surgery department according to evidence-based information from PSS-Policy Brief delineated significant improvement in patient satisfaction from quality of care at a level of 76% for post-intervention group (Post IG) versus 62% among pre-intervention group (Pre-IG) (p<0.005, OR=1.9, CI= 1.2-3.05). There was significant enhancement for ten categories (35 items)of quality of hospital care. Of those quality categories: physicians' performance increased from77% to 85% (p<0.001. OR= 2.2 CI= 1.5-3.02) and nurses' performance increased from 83% to 91% (p=0.001. OR= 3.1 CI= 2.1- 4.4).There was significant reduction in average hospital stay to be ≤ 10 days for 56% of (Post IG) versus 35% among (Pre-IG) (p<0.001). Self-satisfaction from health condition at discharge was reported by 73% of the Post-IG versus 61% of the Pre-IG (p=0.01, OR=1.4 CI= 1.06 – 1.9). The study concluded that PSS used for preparing policy-brief that highlights problems for interventions; and advocate for quality improvement, inspired policy makers to make multidisciplinary interventions for improving quality of health care.