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Pattern of steatosis and histopathological changes in patients with chronic HCV

Thesis

Last updated: 06 Feb 2023

Subjects

-

Tags

Tropical Medicine

Advisors

Salama, Husni M., El-Hendawi, Aly A., Lashin, Sahar E.

Authors

Bahaa-El-Din, Ahmad Muhammad

Accessioned

2017-03-30 06:23:47

Available

2017-03-30 06:23:47

type

M.Sc. Thesis

Abstract

This study was conducted on 27 patients including 21 males and 6 females with chronic hepatitis C virus (HCV) infection and bright liver by Ultrasonography.All 27 patients were subjected to complete history taking, clinical and physical examination, abdominal ultrasonography, laboratory investigations, and liver biopsy.Steatosis was present in liver biopsies of 19 patients (70.4%). Out of these 19 patients, 13 had mild steatosis, 3 had moderate steatosis and 3 had severe steatosis.Body mass index (BMI) and serum albumin were significantly higher in patients with histopathological steatosis compared with those without. In conclusion, hepatic steatosis was highly prevalent in patients with chronic HCV infection and is mild in the majority of cases. It was not related to HCV RNA level and might be due to associated non-alcoholic steatosis or steatohepatitis.

Issued

1 Jan 2006

Details

Type

Thesis

Created At

28 Jan 2023