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A study of postictal sleep architecture in epileptic patients

Thesis

Last updated: 06 Feb 2023

Subjects

-

Tags

Clinical Neurophysiology

Advisors

Abdel-Qader, Ann A., Muhammad, Hatem S., Nada, Muna M.

Authors

Labib, Amira Ahmad

Accessioned

2017-03-30 06:23:43

Available

2017-03-30 06:23:43

type

M.Sc. Thesis

Abstract

The occurrence of seizures can have profound effects on sleep architecture lasting much longer than the postictal period. Seizures affect sleep macroarchitecture and may produce excessive daytime sleepiness (EDS) in patients with epilepsy. Polysomnography has been used to study postictal sleep architecture in epileptic patients whether having generalized or focal epilepsy. We applied PSG recording combined with Long-term Video EEG monitoring for a group of 20 epileptic patients, as well as age and sex matched controls. The recording occurred along 6-8 hours over a night postictally. We utilized a montage formed mainly of 4 channels of EEG, 2 EOG channels, a submental and tibialis EMG channel, an ECG and respiratory monitoring channels. Radiological and laboratory examinations were also carried out for patients to exclude other abnormalities. The recordings were analyzed and staging was done for each subject. Afterwards, Apnea, Hypopnea and PLM indices were found. We found that stage 2 NREM sleep was significantly longer and SWS was significantly shorter in the epileptic group compared to the control group. Also sleep latency to SWS was significantly shorter. We also found that these patients showed less number of awakenings and shorter periods of awake from TST as compared to the control group and thus, they had higher values of sleep efficiency.

Issued

1 Jan 2006

Details

Type

Thesis

Created At

28 Jan 2023