Structural abnormalities of the uterus and endometrial cavity and tubal patency may adversely affect reproductive outcome by interfering with implantation, ovum and sperm transportation and thus causing infertility Hysterosalpingography (HSG) has been used to screen uterine cavity abnormalities and tubal patency. Hysteroscopy has been considered to be the gold standard method for diagnosis of the uterine cavity lesions. The aim of this study was to assess the value of sonohysterography in the diagnosis of uterine intracavitary lesions in infertile females and comparing its diagnostic accuracy with that of hysterosalpingography and transvaginal ultrasonography. 30 infertile females were included in this study after general and gynecological examination. From this study we conclude that sonohysterography is a simple, fast, cost saving, well tolerated and relatively accurate method to evaluate the uterine factor in females with infertility. Sonohysterography offers several advantages over HSG as avoidance of radiation, no use of contrast media and is done in the office by gynecologists.Sonohysterography is recommended as a routine after TVS in cases of suspected intrauterine leiomyomas, polyps, uterine malformations and intrauterine synechia. Routine SHG after TVS can save many unnecessary diagnostic hysteroscopies and helps in the preparation for operative hysteroscopies