Recently, colorectal cancer has been a significant leading cause of death from malignancies worldwide. Conventional open surgery is associated with significant morbidity and long convalescence. Laparoscopic surgery has been widely used as a minimally invasive surgery to treat diverse benign diseases such as benign gall bladder disease. Jacobs et al. first reported the technical feasibility of laparoscopic colectomy in 1991. Since then, laparoscopic surgery has been widely operated for various benign colorectal conditions such as polyps, diverticular disease inflammatory bowel disease, rectal prolapse and now colorectal cancer increasingly. The benefits of laparoscopic surgery in comparison with open surgery have been suggested with respect to decreased morbidity, decreased pain, faster recovery, shorter hospital stay and possibly reduced immunosuppression. Laparoscopic colorectal surgery is technically complex as it involves laparoscopic mobilization of colon over a wide area, intracorporeal division of major vessels, extraction of specimen and a bowel anastomosis. There is a steep learning curve to achieve advanced laparoscopic skills, and specialized equipment is required. Conclusion: In our study, a comparison between 2 Groups each has 20 cases of colorectal cancer in these criteria: Operative time, lymph node yield, resection margins and postoperative stay, postoperative pain, morbidity and mortality. The results showed no significant difference in the lymph node yield, resection margin and mortality. A significant increase in the operative time in the laparoscopic colectomies in comparison to open colectomies, although the mean operative time was progressively decreasing with increasing the number of cases.