Pelvic organ prolapse etiology is multifatorial. The POP-Q in now the only widely accepted to quantify POP objectively. Imaging studies may be useful. Uterovaginal prolapse treatment is vaginal hysterectomy and repair. Post-hysterectomy prolapse treatment is sacro-colpopexy (abdominal or laparoscopic). Prosthetic materials have been used to reduce the high recurrence rates as midvaginal sling or total vaginal mesh.