Beta
41505

Imaging of adrenal gland mass lesions

Thesis

Last updated: 06 Feb 2023

Subjects

-

Tags

Radiology & Nuclear Medicine

Advisors

Hanna, Sameh A. , Badawi, Hesham A. , Mussttafa, Husna , Wahba, Manal H.

Authors

El-Qalyoubi, Muna Muhammad

Accessioned

2017-07-12 06:40:26

Available

2017-07-12 06:40:26

type

M.D. Thesis

Abstract

Our results confirm the evolving role of CT in detection and characterization of an adrenal mass. For a suspected hyperfunctioning adrenal neoplasm, CT should be performed after the appropriate biochemical screening examinations. Further assessment by MRI & localization with MIBG can be done in the setting of pheochromocytoma or neuroblastoma, MIBG scan being helpful to detect any extraadrenal uptake or metastatic deposits & prolonged intense uptake is a clue to a positive diagnosis.When an incidentaloma is detected at imaging a hyperfunctioning lesion should be excluded. If prior imaging is available, stability of the lesion over time is an indicator of benignity over malignancy. If the patient does not have a known 1ry extra adrenal malignancy, the majority of lesions are benign. CT is the next appropriate step. To differentiate a benign adenoma from a metastasis in the oncology patient, nonenhanced CT should be performed. If the attenuation of the adrenal mass is 10 HU or less, the mass is an adenoma and a single follow up CT after 6 months can be advised. If the attenuation is over 10 HU, CECT should be performed and washout calculated. A mean absolute percentage washout of 83% and 41.4% was found in adenomas and metastases respectively while a mean relative percentage washout of 57.4% and 17.95% was found for adenomas and metastases respectively , indicating that adenomas washout contrast more rapidly. If the mass remains indeterminate , MR imaging including CSI should be considered. Significant signal drop on out of phase sequences is impressive of an adenoma. With equivocal CT or MRI, PET and PET CT can also be considered where focal uptake by the lesion exceeding hepatic uptake is classic for malignancy and a mean maximum SUV greater than 3 was found for malignancy. Certain features can be used by the radiologist to establish a definitive diagnosis for an adrenal mass based on imaging findings alone such as the presence of macroscopic fat for myelolipomas and water contents for cysts. Finally percutaneous biopsy might be needed if the lesion remains indeterminate.

Issued

1 Jan 2012

DOI

http://dx.doi.org/10.21473/iknito-space/35442

Details

Type

Thesis

Created At

28 Jan 2023