Objective: This study details assessment of the indications, safety, efficacy and complications of posterior microscopic cervical foraminotomy for treatment of cervical radiculopathy associated with cervical foraminal disc herniation and / or cervical foraminal stenosis of degenerative etiology. Methods: A prospective study conducted on 31patients with unilateral single or double level cervical radiculopathy due to cervical degenerative disc disease confirmed by concordant clinical and radiological data, refractory to non-surgical measures for 3 months at least, admitted and operated at Kasr El-Ainy university hospitals between March 2009 and August 2010. Outcomes were assessed by using the Odom’s criteria. Results: Average age of presentation was 44.1 years, male to female ratio was 1:1.8, and average duration of symptoms was 51.4 weeks. 21 cases had left sided radiculopathy, 10 cases had right sided affection. The most common presenting symptom after brachialgia (100%) was neck pain (87%), most common sign was hyporeflexia (67%). Most common operated level was C5-6 (50%). Excellent and good outcomes were obtained in 87% of the patients. The mean follow up period was 14.5 months with no recurrence, instability or progressive kyphosis. Conclusion: Microscopic posterior cervical foraminotomy is a safe and effective approach for treatment of cervical radiculopathy resulting from foraminal hard and soft disc pathologies with comparable results to the ACDF approach.