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Treatment of melasma with topical vitamin c and trichloroacetic acid versus trichloroacetic acid alone : A comparative study

Thesis

Last updated: 06 Feb 2023

Subjects

-

Tags

Dermatology, Andrology & S.T.D's

Advisors

Sulayman, Muhsen, Ramadhan, Shahira, Basyouni, Dalya

Authors

Nassar, Marwa Abdel-Malek

Accessioned

2017-03-30 06:23:37

Available

2017-03-30 06:23:37

type

M.Sc. Thesis

Abstract

Melasma is an acquired pigmentary disorder with irregular macular lesions that varies from light to dark brown or grey-brown. The face and the other sun exposed areas are the sites of affection. Important probable causes: hormonal factors; as pregnancy and contraceptive pills, sun exposure or idiopathic.Different treatment modalities have been used for the treatment of melasma including: topical treatment using sunscreens, alpha hydroxy acids, retinoids, vitamin C, vitamin E, azelaic acid cream, kojic acid and skin bleaching creams containing hydroquinone 2% and 4%, Chemical peeling using glycolic acid, phenol and trichloroacetic acid (TCA) have been also used. Other treatment modalities include laser and dermabrasion.We treated 30 cases of melasma in our study, all were females. They were all primed with hydroquinone cream, retinoic acid and all were advised to avoid sun exposure as much as possible and use sun screens. Group (A) used trichloroacetic acid as a chemical peeling alone, while we added vitamin C topically in group (B), which showed better results and delayed recurrence.

Issued

1 Jan 2006

Details

Type

Thesis

Created At

28 Jan 2023