Gall stone disease is one of the commonest causes of abdominal pain. Cholecystectomy in the only definitive treatment for this disease. cholecystectomy can be conducted by open method or through laparoscope. One of these complications is gall bladder perforation and spillage of stones within peritoneal cavity. Complications that result from stones are said to occur in 0.08-0.03% of patients. A comparative study was experienced experimentally on dogs to determine the complication which may occur due to spillage of different types of stones within peritoneal cavity. Different stones were collected, sterilized and implanted in the dogs. Complications that occurred were adhesion in all groups but in the third group (infected cholesterol stone) was more extensive. Other complications as persistent fever, abscess formation or intestinal obstruction did not occur in all groups. To conclude complications arising from spillage of gall stones during laparoscopic cholecystectomy are extremely rare. The surgeon should take utmost care to prevent spillage of stones and attempt to remove all visible stones at the time of surgery especially if they are of infected type. Conversion to open technique to retrieve the stones is not indicated.