Emergency EIS was performed on 60 patients with bleeding esophageal varices using either the Ethanolamine Oleate (EO) method or combination of (Histoacryl) and (EO) in the first session, outcome was compared after 6 months follow-up using (EO) as a sclerosing agent in follow-up sessions in both groups. Using combined modality (Histoacryl and EO) was superior to (EO) alone regarding the control of bleeding in first session, prevention of recurrent bleeding, mortality, cost of hospitalization and the incidence of complications.