Biopsy of the kidney is helpful for establishing a diagnosis, monitoring disease progression, assessing prognosis and determining therapy for various kidney diseases.Objectives: To delineate the relation between the clinical picture of various kidneys diseases subjected to kidney biopsy with the pathological results of these biopsies.Methods: Retrospective study , renal biopsies examined by light microscopy between July 1998 and March 2003 in Kasr El Aini Pathological Department