In the last 20 years, there have been important developments in the field of PCI, initially with balloon angioplasty alone and now in combination with coronary stent insertion. In patients scheduled for non-cardiac surgery the risk of MI is increased in the perioperative period so the heart should be protected either by drugs or by preoperative cardia intervention. Coronary artery stents are two types; Bare Metal stents and Drug Eluting stents. Both types of coronary stents require administration of antiplatelet drugs. The management of these type of patients is adilemma. This come from the use of antiplatelet therapy that affects the function of the platelets.