In this study, we aimed to determine the influence of ventilation modes (S-CMV, S-IMV, BIPAP) on the consumption of analgesics and sedatives, duration of intubation and pulmonary gas exchange, a prospective controlled study done on 60 patients who underwent single valve replacement and from the results we concluded that ventilatory support with BIPAP reduces the consumption of analgesics and sedatives, duration of intubation and pulmonary gas exchange. The possible reason is the unrestricted spontaneous breathing in all phases of the respiratory cycle.