Purpose: The evaluation and comparison of the quality of root fillings in teeth with artificial internal resorptive cavities (IRC) using different gutta-percha obturation techniques, namely : Lateral Condensation, System B, Themafil and Obtura II. Materials and methods: Sixty single rooted teeth were selected for this study. The crown of each tooth was removed at the cemento-enamel junction. Canal patency was checked using #15 K-file. Working length was determined by subtracting 1mm from the tooth length. All teeth were instrumented at the working length to #50 K file. Flaring to three sizes larger than the apical instrumentation with 15 strokes on each wall (subtracting 1mm for each larger size). The buccal wall of all teeth was marked before cutting the crowns of the teeth to detect the buccolingual direction of the bur during the preparation of the resorptive defect. The internal resorptive cavity defect was prepared at the middle one third of the canal. The location was determined by adjusting the stopper in the bur at 7 mm shorter than the working length and the location was marked on the outer surface of the tooth. A stainless steel bur of 28 mm length was used for preparation of the resorptive cavities. The bur had a head size 2 which corresponds to a diameter of 1.0 mm. Results: Radiographically the lateral condensation group showed the highest radiopacity. By Stereomicroscope the Obtura II group showed the highest amount of gutta-percha, least amount of sealear and least amount of voids. By Scanning electon microscope the Obtura II group showed the best wall adaptation. Conclusion: The study showed that using Obtura II system in internal resorptive cavities gives the best results in wall adaptation with highest amount of gutta-percha and least amount of sealer and voids. Radiographic evaluation cannot be taken into consideration for evaluating the obturation in endodontics since it does not correlate with the adaptation of the filling and it could not be an indicator for the filling quality.