Hepatic tumors can arise either as hepatocellular carcinoma or by metastasis. Unfortunately most of the hepatic tumors are unresectable at diagnosis and have limited treatment options due to chemoresistance and intolerance of normal liver parenchyma to tumoricidal radiation doses. Radioembolization (RE) is a minimally invasive transcatheter therapy through which radioactive microspheres (Yttrium-90) are infused into hepatic arteries that supply tumor. RE has shown promise for the treatment of unresectable hepatic tumors.