This study aimed to assess whether H. pylori infection has a role in antroduodenal motility in non ulcer dyspepsia patients or not. The interdigestive and post-prandial antroduodenal manometry were studied in (14) patient with non-ulcer dyspepsia (7 patients with H. pylori infection and 7 patients without H. pylori infection) and (14) patients with gastritis (7 patients with H. pylori and 7 patients without H. pylori).The total duration of MMC, the duration of individual phases I, II, III, the antral motility index of phase II, the antral post-prandial motility index and the duodenal motility parameters showed no significant difference between H. pylori positive and H. pylori negative patients. In conclusion H. pylori infection has no effect on antroduodenal motility in patients with non-ulcer dyspepsia.