43435

The study of polymorphism in exon I of the CD152 gene in association with Systemic Lupus Erythematosus

Thesis

Last updated: 06 Feb 2023

Subjects

-

Tags

Clinical and Chemical Pathology

Advisors

Gouhar, Umayma , Mahmoud, Sherin , El-Desouqi, Suha

Authors

Eisa, Amal Husain Khalil

Accessioned

2017-07-12 06:41:59

Available

2017-07-12 06:41:59

type

M.D. Thesis

Abstract

We studied thrity patients with Systemic lupus erythematosus (SLE)and ten healthy control subjects .Our work aimed at studying polymorphism of the CD152 exon-1 gene in association with SLE. Our study showed a higher prevalence of G/G genotype of CD152 exon-1 +49 in patients than in the control subjects [ 25 cases(83.3%) versus 2 controlsubjects(20% )]; p-value <0.05 indicating statistical significance and thatpatients with G/G genotype of CD152 exon-1 +49 are more susceptible todevelop SLE .

Issued

1 Jan 2010

DOI

http://dx.doi.org/10.21473/iknito-space/37372

Details

Type

Thesis

Created At

28 Jan 2023