Thyroid nodules are common clinical lesions with aprevalence of 4 to 7% in the general population. Most are ultimately determined to be benign, but approximately 5% are malignant. Recent literature suggests that each patient withthyroid nodule should undergo a complete evaluation that includes a detailed history and physical examination thesereports suggest that thyroid function tests radioactive scan, andultrasonography add useful information. These measureshowever, cannot distinguish with certainly benign frommalignant lesions. High-risk categories classically are definedby older age, male gender, history of radiation exposure, familyhistory. The presence of a solitary, fixed" cold" hard or growingnodule, hoarseness, lymphadenopathy, fixation, nonregressionwith thyroid hormone treatment, and a solid or complex mass onultrasound.