HCV infection is associated with increased common carotid intima-media thickness (IMT) and carotid-artery plaques in some but not all studies. The aim of this study is to evaluate the relationship between chronic hepatitis C virus (HCV) infection, clearance of HCV and atherosclerosis. It was found that chronic HCV is associated with favourable lipid profile (significant lower serum levels of total cholesterol, TGs and LDL-c). It was also associated with significant higher mesenteric fat thickness and non significant increase in the carotid IMT.