BIS index is an FDA approved monitor for assessing the sleep/awake status for patients, BIS monitor is a non invasive device that is easily applied to the forehead, it can be applied in all ages, sex, various medicaland surgical situations. The use of BIS guided anesthesia can aid in adjusting anesthetic agents required for induction of anesthesia that is sufficient to blunt the stress response accompanying larygoscopy and intubation, maintenance and recovery of anesthesia. BIS benefits can be extended far beyond OR and can be used in the ICU to help in providing sedation and analgesia.