In cases of renal failure, renal replacement aims to remove toxins & achieve water, electrolytes & acid‐base homeostasis. Acute peritoneal dialysis has many advantages, particularly in children, since it is less demanding an equipment & experience & lack of need for vascular access & anticoagulation.Removals of fluids, urea & creatinine as well as correction of acidosis and potassium were studied in 21 patients (age from 3months to 14years) undergoing acute peritoneal dialysis for mean duration of 53 hours.The mean kT/V (urea) of 1.3 & creatinine clearance was 14.6L/1.73m2. ultrafiltration reached 303 ml/kg, with mean of 86 ml/kg . ultrashort (5‐10 min) dwells improved ultrafiltration & acidosis correction, with similar clearance of urea & creatinine, Increasing run volumes improved creatinine clearance.APD is needed & useful in infants & children requiring acute renal replacement.