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Stereotactic radiosurgery for brain metastasis

Thesis

Last updated: 06 Feb 2023

Subjects

-

Tags

Neurosurgery

Advisors

Zuhdi, Ahmad Z. , Abdel-Qader, Yaser S. , Ramadhan, Muhammad H. , Redha, Wael A.

Authors

Muhammad, Muhammad Zakareya

Accessioned

2017-07-12 06:40:19

Available

2017-07-12 06:40:19

type

M.D. Thesis

Abstract

Stereotactic radiosurgery is a minimally invasive, single session, high-dose, closed skull strategy that may be especially suitable for patients who have limited metastatic brain disease and have controlled systemic disease with good functional status. The optimal dose range for volumetric conformal Stereotactic brain metastases radiosurgery has been largely established based on tumor anatomy (proximity to eloquent brain regions), tumor volume, and prior radiation therapy and estimated adverse radiation risks. Minimum doses to the margin range from 12-25Gy in a single session.Post-radiosurgical clinical examinations and MR studies are requested by referring physicians at 2-3 month intervals or earlier if the patient develops a new symptom suggestive of a new tumor, brain edema or hemorrhage.Causes for local failure of Stereotactic radiosurgery include inadequate visualization of the tumor, lack of intraoperative Stereotactic 3-D (volumetric) imaging, new metastatic deposits and insufficient dose (due to large tumor volume and proximity to eloquent brain locations) to achieve the growth control response.

Issued

1 Jan 2012

DOI

http://dx.doi.org/10.21473/iknito-space/35294

Details

Type

Thesis

Created At

28 Jan 2023