Single-incision laparoscopic surgery (SILS) has recently emerged as a new technique intending to minimize surgical trauma and improving cosmeses. (Jaksa et al., 2009)Technological innovations and increased surgical experience with laparoscopy have advanced the field of complex laparoscopic surgery to include operations for colorectal diseases. While the laparoscopic approach decreases surgical morbidity, it still requires three to four incisions each is ≥1-2 cm long. In addition, each working port risks morbidity from bleeding, hernia, and/or internal organ damage, and incrementally decreases cosmeses. (Anish et al., 2010)The aim of this work is to assess the outcome of using the Single-incision Laparoscopic Surgery (SILS) in the field of colorectal diseases.This study contains twenty cases of colorectal diseases, done in the surgical colorectal unit in Kasr ElAini hospital in 2011.Three cases were converted to conventional open procedure, one due to extensive adhesions and a presence of a rectovaginal fistula due to Crohn’s disease; the other one due to extensive uncontrollable bleeding of the mesentry of the colon during right hemicolectomy and the third one due to technical difficulties.Results were satisfying and promising to encourage the use of the SILS in colorectal diseases safely and effectively.