General Measures to prevent renal dysfunction after Cardiac Surgery should be utilized in all patients with special attention to those with preoperative renal dysfunction.Regarding postoperative renal dysfunction and need for dialysis, results were in favor of the off-pump technique.Renal function is better preserved in patients undergoing off-pump CABG than those undergoing on-pump CABG.CPB is associated with a higher risk for PRD, and this injury is associated further with substantial morbidity and mortality.At present, no pharmacologic interventions have demonstrated conclusively efficacy in the prevention of renal dysfunction after cardiac surgery.