The aim of our study is to asses the efficiency of pulse oximeter as ascreening tool of peripheral arterial disease. Our study enrolled 150 patients, 50 patients above age of 60 year without symptoms of PVD, 50 asymptomatic patients with low ABI and 50 patients having symptomatic PVD. Duplex study of lower limbs, ABI measurement and oxygen saturation difference between index finger and toe were done to every patient. We considered abnormal pulse oximerter of the toes as a SaO2 value of more than 2% lower than the fingers value or a decrease of more than 2%on elevation of the leg (decrease from the value at the supine position),abnormal ABI < 0.9.We found good correlation between pulse oximerter result and ABI as itcan detect (82.8%) of diseased limbs detected by ABI and (86.7%) of normal limbs detected by ABI. Pulse oximerter seems to be valuable since it can be performed in outpatient clinics and handle large numbers of patients in a short time and avoid the problem of media sclerosis. We found that pulse oximeter was highly sensitive (85%) to detect lower limb ischemia detected by duplex also it was highly specific (96.4%) to exclude lower limb ischemia excluded by duplex