Laser surgery of the upper airway is performed endoscopically under the microscope. One of the advantages of this type of surgery over an open partial technique is that it only removes the lesion, preserving larger adjacent free areas and maintaining the laryngeal skeleton closed. The functional results may also improve, and most patients do not require a tracheotomy. However, because of the increase in the use of this technique for laryngeal and hypopharyngeal lesions, a greater number of complications may be expected. The aim of this study was to evaluate the incidence, type, and clinical significance of intraoperative and postoperative complications of upper airway lesions treated with laser surgery.