A lot of data emphasized the immunostimulatory role of supplemental glutamine. Increased counts of circulating total lymphocytes and enhanced T-cell lymphocyte synthesis are consistently found in stressed patients following provision of glutamine. Therefore, if a conditional deficiency occurs in critically ill patients, replacement with glutamine is mandatory. From here, we started the idea of our research which was concerned with studying the effect of parenteral glutamine supplementation in addition to conventional nutritional intake on the clinical outcome of patients suffering from abdominal sepsis. By the time the study was done, there were no adequate studies for the effects of glutamine in patients suffering from abdominal sepsis.