Objective:The present study was designed to compare between colour Doppler and computed tomography in evaluation of cervical lymph nodes in patients with laryngeal and hypopharyngeal carcinomas.Materials and methods:This study included thirty patients with known primary laryngeal and/or hypopharyngeal carcinomas with non palpable (N0) or palpable lymph nodes who were referred to the department of Otorhinolaryngology, Kasr El-Aini Hospital from August 2009 to April 2011. The material consisted of 24 men and 6 women, their age ranged from 34-72 years.Results:Computed tomography findings were on the right side 4 positive cases and 26 negative cases while on the left side there were 6 positive cases and 24 negative cases. With sensitivity on right side (50%), on left side (62.5%) and mean (56.3%), specificity on right side (95.8%), on left side (95.5%) and mean (95.6%), positive predictive value on right side (75%), on left side (83.3%) and mean (79.2%), negative predictive value on right side (88.5%), on left side (87.5%) and mean (88%) and overall accuracy on right side (86.7%), on left side (86.7%) and mean (86.7%). Colour Doppler findings were on the right side 5 positive cases and 25 negative cases while on the left side there were 7 positive cases and 23 negative cases. With sensitivity on right side (66.7%), on left side (75%) and mean (70.9%), specificity on right side (95.8%), on left side (95.5%) and mean (95.6%), positive predictive value on right side (80%), on left side (85.7%) and mean (82.9%), negative predictive value on right side (92%), on left side (91.3%) and mean (91.7%) and overall accuracy on right side (90%), on left side (90%) and mean (90%). Conclusion:In our study, all of the findings suggested superiority of the colour Doppler investigation. the present study appreciates the important role of colour Doppler in the diagnostic approach to cervical lymphadenopathy. Although colour Doppler evaluation cannot replace histopathological procedure in knowing the status of cervical lymphadenopathy, it plays a definite role as an adjunct to the clinical evaluation of cervical lymphadenopathy and proves its value as an important investigation for differentiating between benign and malignant lymphadenopathy.